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Immobilized β-Galactosidase-Mediated Conversion of Lactose: Process, Kinetics and Modeling Studies

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Immobilized β-Galactosidase-Mediated Conversion of Lactose: Process, Kinetics and Modeling Studies
KETAB DOWNLOAD

Immobilized β-Galactosidase-Mediated Conversion of Lactose: Process, Kinetics and Modeling Studies

19.00$

Author(s)Fadzil Noor Gonawan
Year2019
Pages186
LanguageEnglish
FormatPDF
Size6 MB
PublisherSpringer
ISBN9811334676, 978-9811334672, B07MQ382F1

This book describes the reaction rate profiles of the β-galactosidase-catalyzed conversion of lactose on the inner surface of a hollow fiber membrane, which is employed as an enzymatic reactor system. The reaction rate profiles were obtained by solving the mass transfer and kinetics of reaction in a 2-dimensional model of the system. The primary challenge of this research was to develop the kinetic model of the reaction to describe the kinetic behavior as the reaction occurred on the membrane surface. Despite the difficulties, the proposed model can reliably replicate the actual process, as validation procedures have confirmed.

The reaction rates obtained analyze the performance of the immobilized enzyme on the membrane surface. Previously, an increase in performance of 'β-galactosidase-catalyzed conversion of lactose assisted by ultrafiltration was suggested due to inhibitor removal. However, as the analysis presented here shows, the concentration profile of the substrate on the membrane surface also affects the reaction performance.