In the name of of Allah the Merciful

Varicella-zoster Virus: Genetics, Pathogenesis and Immunity

Current Topics in Microbiology and Immunology, Ann M. Arvin, Jennifer F. Moffat, Allison Abendroth, Stefan L Oliver, 3031153049, 978-3031153044, 9783031153044, 978-3031153051, 9783031153051, B0BL6W3K35

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English | 2022 | PDF

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This edited volume provides insights about the molecular virology,  pathoenesis of infection and host responses to varicella-zoster virus,  which is a medically important human herpesvirus.  The chapters not only  discuss genetics and molecular evolution of the virus, but also new  structure-based knowledge on the functions of viral glycoproteins.  Further, the authors illustrate how mechanisms from the virus are used  to take over and remodel host cells during pathogeneis. These mechanisms  also enable viral modulation of host cells and evasion of the host  immune response. Part of these evasion and survival strategies, is the  reaction to triggered host cell responses like autophagy, the stress  response, modulation of apoptosis and other cell death pathways.

This hands-on knowledge is crucial for students and clinicians in Virology, Immunology, and Infectious Diseases.